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Get to Know Patellofemoral Pain Syndrome (Runner's Knee)

Get to Know Patellofemoral Pain Syndrome (Runner’s Knee): A Condition That Doesn’t Only Affect Athletes

Patellofemoral pain treatment (PFPS) is essential for managing what’s commonly known as Runner’s Knee—a condition that affects not only athletes but also people with active or repetitive lifestyles. Understanding the causes, symptoms, and treatment options can help reduce pain, improve knee function, and prevent future issues.

What Is Patellofemoral Pain Syndrome (PFPS)?

PFPS occurs when the cartilage behind the kneecap (patella) becomes inflamed or deteriorated, causing pain and restricted movement. It is commonly seen in people who overuse their knees or apply frequent pressure to the area — including runners, but also:

  • Office workers who sit for extended periods
  • Long-distance drivers
  • Individuals who frequently climb stairs or kneel
  • Older adults experiencing natural cartilage wear
Runner's Knee, may be caused by..

Causes of PFPS

While PFPS is often associated with aging, it can also affect younger adults due to the following risk factors:

  • Direct trauma to the kneecap from falls or impact
  • Overuse or repetitive motion, such as frequent running, jumping, or prolonged sitting
  • Muscle imbalance, especially weakness in the muscles around the knee
  • Excess body weight causing increased pressure on the knee
  • Aging, which contributes to cartilage degeneration
  • Sports injuries or poor exercise technique

Symptoms of Runner’s Knee

Patients with PFPS may experience pain around the front of the knee and other warning signs, including:

  • Pain when sitting for a long time or climbing stairs
  • A grinding or crackling sound when bending the knee
  • Sudden sharp pain during movement or exercise
  • Swelling or inflammation around the knee joint

Patellofemoral Pain Treatment Options

Treatment methods for PFPS vary depending on the severity of the condition. Common approaches include:

1. Initial Self-Care

If you experience mild pain or discomfort, it is recommended to:

  • Avoid activities that place excessive impact on the knees
  • Apply ice to reduce inflammation
  • Do gentle exercises to strengthen the thigh and knee muscles

2. Medication and Physical Therapy

If the condition becomes more severe, a doctor may recommend:

  • Anti-inflammatory medication (NSAIDs) to relieve pain and swelling
  • Physical therapy to improve muscle balance and joint stability

3. Stem Cell Therapy (Advanced Option)

Mesenchymal Stem Cell (MSC) Therapy is an innovative treatment showing promising results in restoring damaged cartilage and reducing knee inflammation. MSCs, derived from bone marrow, fat, or umbilical cord, can:

  • Support cartilage regeneration
  • Decrease joint inflammation
  • Promote tissue repair and improve overall joint function

This therapy is currently under clinical study and should always be considered under professional medical guidance.

Prevention and Knee Health Tips

To reduce the risk of developing PFPS or prevent its recurrence:

  • Avoid high-impact exercises without proper footwear
  • Maintain a healthy weight to reduce stress on the knees
  • Regularly strengthen the thigh and surrounding muscles
  • Avoid prolonged kneeling or sitting with bent knees
  • Eat foods that promote joint health, such as those rich in collagen, vitamin D, and calcium

About EDNA Wellness

Located in Bangkok, EDNA Wellness is a private clinic specializing in Stem Cell Therapy for Neurology & Stroke as well as Bones & Joints. Beyond rehabilitation, we also provide aesthetic and wellness treatments to support your full-body vitality — all delivered with expert care and compassion.

For more information or inquiries, contact us via

LINE @ednawellness

WhatsApp +66 (0) 64 505 5599

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