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Understand What is Patellofemoral Pain Syndrome (Runner’s Knee) and How Stem Cells Can Help ?

Patellofemoral Pain Syndrome (PFPS), also known as “Runner’s Knee,” is more common than most people think — and not just among athletes. It frequently affects working-age adults who sit for long periods, drive frequently, or engage in repetitive movements that stress the knees. If left untreated, it can lead to chronic pain and joint degeneration.

What Is Patellofemoral Pain Syndrome (PFPS)?

Patellofemoral Pain Syndrome is a condition involving the softening and inflammation of the cartilage behind the kneecap (patella). This irritation can result in pain, stiffness, and friction during movement, especially when sitting, climbing stairs, running, or kneeling. While often associated with runners, PFPS is also seen in

  • Office workers who sit for hours
  • Drivers on long commutes
  •  Individuals who frequently lift or carry heavy loads
  • Older adults with age-related cartilage wear

What Causes Runner’s Knee?

PFPS is often triggered by multiple factors, including:

  • Direct impact to the knee (e.g., falling or hitting the kneecap)
  • Repetitive stress from running, jumping, or prolonged sitting
  • Muscle imbalances around the knee and thigh
  • Excess body weight increase pressure on the knee joint
  • Age-related cartilage degeneration
  • Previous injuries or improper exercise form

Runner's Knee, may be caused by..
This might be the reason why your knee is hurt

Common Symptoms to Watch For

If you’re experiencing these signs, it might be time to consult a specialist:

  • Pain at the front of the knee, especially after sitting or stair climbing
  • Grinding or popping sounds when bending the knee
  • Swelling or a sharp, stabbing sensation during movement
  • Sensitivity during workouts or physical activities

Treatment Options

Treatment for PFPS ranges from simple behavior changes to advanced therapies depending on the severity:

1. Conservative Management

  • Avoid high-impact activity
  • Ice application for inflammation
  • Quadriceps and hamstring strengthening exercises

2. Medication & Physical Therapy

  • NSAIDs to relieve pain and swelling
  • Supervised physiotherapy to correct movement patterns and build stability

3. Stem Cell Therapy for Knee Regeneration

Mesenchymal Stem Cells (MSCs) are now being used to support cartilage repair and reduce joint inflammation. Studies show MSCs help:

  • Regenerate damaged cartilage tissue
  • Reduce chronic knee inflammation
  • Improve mobility and long-term joint health

This approach is under active clinical research and may not be suitable for all cases. Always consult a qualified physician

How to Prevent or Reduce Risk of Runner’s Knee

You don’t need to be an athlete to care for your knees. Here’s how you can minimize your risk:

  • Avoid repetitive high-impact movements (e.g., jumping without cushioning shoes)
  • Maintain a healthy weight to reduce joint pressure
  • Strengthen quadriceps, hamstrings, and surrounding muscles
  • Use ergonomic posture and avoid prolonged knee bending
  • Eat a joint-friendly diet rich in collagen, calcium, and vitamin D

About EDNA Wellness

Located in Bangkok, EDNA Wellness is a private clinic specializing in Stem Cell Therapy for Neurology & Stroke as well as Bones & Joints. Beyond rehabilitation, we also provide aesthetic and wellness treatments to support your full-body vitality — all delivered with expert care and compassion.

For more information or inquiries, contact us via

LINE @ednawellness

WhatsApp +66 (0) 64 505 5599

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